Should i calibrate my mavic pro before i use it for the first time since it's still in the box?

Which calibration are you referring to?

Yes. Calibrate the compass and the IMU.

Hi Charbel, may I know what calibration you are referring to? For the compass, here are some scenarios that we suggest calibrating it:
1. When compass data is abnormal, and the Aircraft Status Indicator is blinking red and yellow.
2. When flying in a new location, or a location that is different from your last flight.
3. When the aircraft moves erratically during flight, i.e. the drone doesn't fly in straight lines.
You can go this route: MC Settings--Advanced Settings--Sensor--Compass--calibrate.
For the IMU calibration you can calibrate the IMU before each flight but please ensure you do the calibration on a flat surface.Click on "Reply" so that I can receive a notification from your response. Thanks for your support.