Unfortunately 4.2.20 does not fix the issue with the disabled buttons once Point of Interest mode is engaged on my Mavic Air.

Check here and you are right it did not.  I have an open dji support case and they are aware of and working on a fix.  https://forum.dji.com/thread-150560-1-1.html

SparksBird Posted at 2018-6-9 18:21
Check here and you are right it did not.  I have an open dji support case and they are aware of and working on a fix.  https://forum.dji.com/thread-150560-1-1.html

So far 50% of the voters have the problem and still not a word from DJI...

nywrecker Posted at 2018-6-10 04:58
So far 50% of the voters have the problem and still not a word from DJI...

The DJI rep that I opened up the case with has been responding back to me.  He said he still has no update and the last update from the Engineering team is they have replicated the issue and are working on a resolution but no time table when there will be a resolution.  So basically waiting on them to fix the issue but at least they are aware of it.  He said I will get updated as soon as they have a fix so I should/hopefully will be the first to know.

nywrecker Posted at 2018-6-10 04:58
So far 50% of the voters have the problem and still not a word from DJI...

I am betting the 50% of the voters that voted no issue are android users as it does not appear to be an android issue but strictly IOS.