I'm wondering if there is any signal interference with the antenna because the iPad or what ever device you use sits up near the antenna.

Hi Jake, generally speaking, the interference from the mobile device can be ignored. The main interference is from environment, such as WiFi signal , wires or buildings, metal, etc.
You could put the device into flight mode so that no calls interrupt you during the flight.
And here is a tutorial for you if needed:

Natalia, Thanks for the reply, I've watched the video a couple times before I used my P3. My iPad is only used for the P3, it has no phone capabilities, or needless apps, just DGI Go. The question was more of a curiosity seeing the devices are in close proximity of the antenna's. Thanks again, you did answer my question.