In 1937 “Instituto” began to operate, studying the hydrobiology, the sponges and fisheries of the Aegean sea and hosting an aquarium with interesting species of the marine fauna of the Mediterranean.
Designed by Armando Bernabiti, the building combines local with Art Deco architectural elements of curved lines and circular windows, along with a dominant cylindrical tower. The decoration of the main entrance was inspired from the marine environment. The Aquarium consists of a corridor, with small tanks that host marine species and it is made of stone and decorated with natural shells, featuring an underwater cave, while the floor is paved by white and black pebbles, featuring marine species.
The Greek Ministry of Culture has characterised Hydrobiological Station of Rhodes’ building as an historical landmark and a distinguished sample of “Eclecticism” and "International" architectural style.